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pentobarbital will decrease the extent or impact of etravirine by influencing hepatic enzyme CYP2C9/10 metabolism. Use Caution/Observe.Contraindicated (one)pentobarbital decreases amounts of panobinostat by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Contraindicated. Solid CYP3A4 inducers can minimize panobinostat levels by ~70% and resu